Home News "Once Human: Top PvE & PvP Builds, Weapons, Gear"

"Once Human: Top PvE & PvP Builds, Weapons, Gear"

by Penelope May 12,2025

In Once Human, your gear and weapon choices are the cornerstone of your battle prowess. Whether you're tackling corrupted beasts in PvE zones or launching raids on player settlements in PvP, a well-synergized build is crucial for not just surviving but thriving.

This comprehensive guide delves into four of the most potent builds available in the latest version of Once Human. We provide in-depth insights into weapons, gear modifications, synergy effects, and tactical playstyle tips. Our analysis spans from builds optimized for Area of Effect (AoE) clearing to those designed for Damage over Time (DoT) and critical burst damage, ensuring they are effective for both solo adventurers and team players.

New to the game? Make sure to visit our Beginner’s Guide for Once Human for a thorough introduction!

Once Human Gameplay

Final Tips for Optimizing Your Build

  • Sync weapon effects and mods: Select gear that amplifies your weapon's elemental or status effects to maximize your damage output.
  • Keep upgrading: The rarity and enhancement level of your gear significantly influence its effectiveness. Always strive to keep your equipment up-to-date.
  • Craft backup loadouts: Prepare a secondary build focused on different elements to effectively counter various mutant types or adapt to PvP strategies.

Each build in Once Human is tailored for specific scenarios, be it tackling boss fights, clearing waves of enemies, or executing swift PvP takedowns. Experiment with different loadouts, fine-tune your gear mods, and switch builds based on the mission type or the resistance of your enemies.

For an unparalleled gaming experience—featuring lag-free aiming, efficient multi-instance farming, and swift inventory management—consider playing Once Human on BlueStacks. Enhance your gameplay with complete control support and enjoy ultra-smooth frame rates.